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Compound 1769-24-0
CAS No. 1769-24-0
Compound 1769-24-0( —— )
Catalog No. M37931 CAS No. 1769-24-0
Compound 1769-24-0 is a natural product for research related to life sciences. The catalog number is TPL0186 and the CAS number is 1769-24-0.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 200MG | 26 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCompound 1769-24-0
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NoteResearch use only, not for human use.
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Brief DescriptionCompound 1769-24-0 is a natural product for research related to life sciences. The catalog number is TPL0186 and the CAS number is 1769-24-0.
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Description2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM.
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In Vitro2-Methylquinazolin-4-ol inhibits ATCase in a concentration-dependent manner.
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In Vivo2-Methylquinazolin-4-ol (0.2-1 mg; i.g.; for two days) inhibits ATCase in a dosedependent manner in vivo.Animal Model:Mice Dosage:0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 1 mg Administration:Oral gavage, for two days Result:Showed an inhibitory effect upon ATCase.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1769-24-0
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Formula Weight160.17
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Molecular FormulaC9H8N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (312.17 mM; Ultrasonic ) H2O : < 0.1 mg/mL (insoluble)
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SMILESCC1=NC2=CC=CC=C2C(=O)N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. S Yoshida, et al. Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly(ADP-ribose) synthetase, by bacterium. J Antibiot (Tokyo). 1991 Jan;44(1):111-2.?
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